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Mainz is the state capital of Rhineland-Palatinate and home to Schott, Werner & Mertz and BioNTech. The University Medical Center employs around 9,000 people, and the ZDF broadcaster is based on the Lerchenberg. The A60 and A643 cross the Rhine on their own bridges into Hesse, and the S8 suburban rail line runs to Frankfurt Airport without a change.
Industrial companies are located mainly between the city centre and Mombach, including the specialty glass manufacturer Schott with its main plant in the Neustadt and the cleaning products manufacturer Werner & Mertz. BioNTech has its headquarters in the Oberstadt, the University Medical Center employs around 9,000 people, and the ZDF on the Lerchenberg had almost 3,900 permanent employees at the end of 2023. The Hechtsheim industrial area lies on the Mainz motorway ring with the junctions Mainz-Hechtsheim-West and Mainz-Hechtsheim-Ost, and the Kisselberg industrial area is in Gonsenheim. The A60 also has the junctions Mainz-Finthen, Mainz-Lerchenberg, Mainz-Weisenau and Mainz-Laubenheim, and the A63 begins at the Kreuz Mainz-Süd interchange towards Alzey. The A643 runs via Mainz-Gonsenheim and Mainz-Mombach to the Schiersteiner Brücke towards Wiesbaden. The S8 stops at Mainz Nord, the Hauptbahnhof and Römisches Theater, and continues via the airport to Frankfurt.
The airport is around 25 kilometres away. Long-distance and regional trains run from Mainz Hauptbahnhof several times an hour, and the journey takes about 25 minutes. The S8 suburban rail line runs without a change.
The A60 runs as a half ring between the inner and outer districts, with junctions in Finthen, Lerchenberg, Hechtsheim, Weisenau and Laubenheim, and crosses into Hesse via the Weisenauer Brücke. The A63 begins at the Kreuz Mainz-Süd interchange and heads towards Alzey and Kaiserslautern. The A643 crosses the Schiersteiner Brücke to Wiesbaden.
Schott, Werner & Mertz and BioNTech have their headquarters in Mainz. The University Medical Center employs around 9,000 people, and the ZDF had almost 3,900 permanent employees at the end of 2023.