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Wiesbaden is the state capital of Hesse and home to the Federal Statistical Office, the Federal Criminal Police Office and R+V Versicherung. About 5,800 people work at around 75 companies in the Industriepark Wiesbaden am Rhein, the former Kalle-Albert plant. Since August 2025, both halves of the new Salzbachtal Bridge on the A66 have been open to traffic, and three S-Bahn lines run to Frankfurt, two of them via the airport.


In the Industriepark Wiesbaden, the former Kalle-Albert plant in Biebrich and Amöneburg, about 5,800 people work on 96 hectares at around 75 companies, including Kalle, SE Tylose and Mitsubishi Polyester Film. Right next to it are the Dyckerhoff plants, and SGL Carbon has its headquarters in Schierstein. Other commercial areas named by the city include Petersweg in Kastel, Äppelallee in Biebrich, Kreuzberger Ring in Erbenheim, Borsigstraße in Nordenstadt and the Max-Planck-Park in Delkenheim. The A66 has the junctions Wiesbaden-Biebrich, Wiesbaden-Mainzer Straße, Wiesbaden-Erbenheim and Wiesbaden-Nordenstadt and meets the A3 at the Wiesbadener Kreuz. At the Schiersteiner Kreuz, the A643 branches off over the Schierstein Bridge to Mainz, and at the Mainzer Straße junction the A671 leads to Hochheim. The main station is the terminus of the S-Bahn lines S1, S8 and S9 and is connected to the ICE network.
The airport is about 25 kilometres away. From the main station, the S1 runs to Frankfurt via Höchst. The S8 (via Mainz) and the S9 (via Mainz-Kastel) stop at the airport and continue to Frankfurt. By road, the A66 leads to Frankfurt, and the airport can be reached via the Wiesbadener Kreuz and the A3.
The old Salzbachtal Bridge on the A66 in Biebrich was closed and demolished by controlled explosion in 2021. The new bridge has been open with both halves since 1 August 2025, with two lanes in each direction. The new Schierstein Bridge on the A643 to Mainz has been complete since August 2023.
Wiesbaden is home to the Federal Statistical Office, the Federal Criminal Police Office and R+V Versicherung. SGL Carbon has its headquarters in Schierstein, and about 5,800 people work at around 75 companies in the chemicals, pharmaceuticals, food and packaging sectors in the Industriepark Wiesbaden.